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Tutorials

Clustering

For getting started, we recommend Scanpy’s reimplementation :tutorial:`pbmc3k` of Seurat’s [Satija15]_ clustering tutorial for 3k PBMCs from 10x Genomics, containing preprocessing, clustering and the identification of cell types via known marker genes.

_static/img/tutorials/170505_seurat/filter_genes_dispersion.png

_static/img/tutorials/170505_seurat/louvain.png

_static/img/tutorials/170505_seurat/NKG7.png

_static/img/tutorials/170505_seurat/violin.png

_static/img/tutorials/170505_seurat/cell_types.png

Visualization

This tutorial shows how to visually explore genes using scanpy. :tutorial:`plotting/core`

_static/img/stacked_violin_dotplot_matrixplot.png

Trajectory inference

Get started with the following example for hematopoiesis for data of [Paul15]_: :tutorial:`paga-paul15`

_static/img/tutorials/paga_paul15.png

More examples for trajectory inference on complex datasets can be found in the PAGA repository [Wolf19]_, for instance, multi-resolution analyses of whole animals, such as for planaria for data of [Plass18]_.

_static/img/tutorials/paga_planaria.png

As a reference for simple pseudotime analyses, we provide the diffusion pseudotime (DPT) analyses of [Haghverdi16]_ for two hematopoiesis datasets: DPT example 1 [Paul15]_ and DPT example 2 [Moignard15]_.

Integrating datasets

Map labels and embeddings of reference data to new data: :tutorial:`integrating-data-using-ingest`

https://scanpy-tutorials.readthedocs.io/en/latest/_images/integrating-data-using-ingest_21_0.png

Spatial data

_static/img/spatial-basic-analysis.png

Further Tutorials

Conversion: AnnData, SingleCellExperiment, and Seurat objects

https://github.com/theislab/scanpy-in-R/raw/master/logo.png

Regressing out cell cycle

See the cell cycle notebook.

_static/img/tutorials/170522_visualizing_one_million_cells/tsne_1.3M.png

Scaling Computations

Simulations

Simulating single cells using literature-curated gene regulatory networks [Wittmann09]_.

_static/img/tutorials/170430_krumsiek11/timeseries.png

Images

See pseudotime-time inference on deep-learning based features for cell cycle reconstruction from image data [Eulenberg17]_.