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DESCRIPTION
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Package: miloR
Type: Package
Title: Differential neighbourhood abundance testing on a graph
Version: 1.3.4
Authors@R:
c(person("Mike", "Morgan", role=c("aut", "cre"), email="[email protected]"),
person("Emma", "Dann", role=c("aut", "ctb"), email="[email protected]"))
Description: Milo performs single-cell differential abundance testing. Cell states are modelled
as representative neighbourhoods on a nearest neighbour graph. Hypothesis testing is performed using a
negative bionomial generalized linear model.
License: GPL-3 + file LICENSE
Encoding: UTF-8
URL: https://marionilab.github.io/miloR
BugReports: https://github.com/MarioniLab/miloR/issues
biocViews: SingleCell, MultipleComparison, FunctionalGenomics, Software
Depends: R (>= 4.0.0),
edgeR
Imports: BiocNeighbors,
BiocGenerics,
SingleCellExperiment,
Matrix (>= 1.3-0),
S4Vectors,
stats,
stringr,
methods,
igraph,
irlba,
cowplot,
BiocParallel,
BiocSingular,
limma,
ggplot2,
tibble,
matrixStats,
ggraph,
gtools,
SummarizedExperiment,
patchwork,
tidyr,
dplyr,
ggrepel,
ggbeeswarm,
RColorBrewer,
grDevices
Suggests:
testthat,
MASS,
mvtnorm,
scater,
scran,
covr,
knitr,
rmarkdown,
uwot,
BiocStyle,
MouseGastrulationData,
MouseThymusAgeing,
magick,
RCurl,
curl,
graphics
RoxygenNote: 7.1.2
NeedsCompilation: no
Packaged: 2020-07-31 14:15:28 UTC; morgan02
Collate:
'AllClasses.R'
'AllGenerics.R'
'buildFromAdjacency.R'
'buildGraph.R'
'calcNhoodExpression.R'
'calcNhoodDistance.R'
'countCells.R'
'findNhoodMarkers.R'
'graphSpatialFDR.R'
'makeNhoods.R'
'milo.R'
'miloR-package.R'
'methods.R'
'plotNhoods.R'
'sim_discrete.R'
'sim_trajectory.R'
'testNhoods.R'
'testDiffExp.R'
'utils.R'
'buildNhoodGraph.R'
'annotateNhoods.R'
'groupNhoods.R'
'findNhoodGroupMarkers.R'
VignetteBuilder: knitr