Molten output relative only to one sequence?

[tseemann]

Would be good to do molten output relative to a ref seq, either provided, or by ID, or the 1st seq in the alignment?

O(N) work instead of O(N^2) and discarding.

[zx8754]

Is this a related post?

• https://www.biostars.org/p/468079/

Where they want to keep only unique rows, based on seq1 and seq2, regardless of order. Basically, melting a matrix that has upper or lower triangle set to NA.