Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Well phenotype probability comparisons #15

Merged
merged 7 commits into from
Nov 29, 2023

Conversation

MattsonCam
Copy link
Member

@MattsonCam MattsonCam commented Nov 21, 2023

In this pr, the predicted probabilities of phenotypes are compared between treated wells and the negative control(s). This is accomplished by comparing the predicted probabilities of cells in each treatment well with cells in the control wells. Stratified sampling of cells from control wells ensure a proportionate representation of cell populations during these comparisons. Wells with a cell count bellow 50 are disregarded. To create the comparisons I performed a KS test between the respective control and treatment probability distributions. Another pr will be created to update the README and possibly other intermediary scripts. Please let me know if you have any questions or suggestions.

Copy link

Check out this pull request on  ReviewNB

See visual diffs & provide feedback on Jupyter Notebooks.


Powered by ReviewNB

Copy link
Member

@MikeLippincott MikeLippincott left a comment

Choose a reason for hiding this comment

The reason will be displayed to describe this comment to others. Learn more.

Great clean PR! Consider making edits in the documentation sections of the functions specifically adding summaries to the docstrings stating what the purpose of the function is. Also, consider adding type hints to the functions.

I think if you choose to apply these edits, they are pretty straight forward so I am going to approve this PR, but please let me know if you want me to take another look?

@MattsonCam
Copy link
Member Author

Thanks Mike, merging now!

@MattsonCam MattsonCam merged commit 458754f into main Nov 29, 2023
@MattsonCam MattsonCam deleted the well_phenotype_probability_comparisons branch December 11, 2023 23:52
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

Successfully merging this pull request may close these issues.

2 participants