SCONE (Single-Cell Overview of Normalized Expression), a package for single-cell RNA-seq data quality control (QC) and normalization. This data-driven framework uses summaries of expression data to assess the efficacy of normalization workflows.
The easiest way to install the package is to type in R
source("https://bioconductor.org/biocLite.R")
biocLite("devtools")
biocLite("YosefLab/scone", dependencies=TRUE)
Note that SCONE requires R (>= 3.3) and Bioconductor (>= 3.3). You can download the latest version of R from CRAN. To update Bioconductor to its latest release, follow the instructions here.