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MpsLDA-ProSVM: predicting multi-label protein subcellular localization by wMLDAe dimensionality reduction and ProSVM classifier

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##MpsLDA-ProSVM

predicting multi-label protein subcellular localization by wMLDAe dimensionality reduction and ProSVM classifier

###Guiding principles:

**The dataset file contains Gram-negative bacteria dataset, Gram-positive bacteria dataset , plant dataset and virus dataset.

**Feature extraction

  1. Evolutionary information: psepssm.m is the implementation of PsePSSM.
  2. Physicochemical_information: PAAC.m,mainpseaac.m is the implementation of PseAAC.
  3. Sequence_information: CTriad.py is the implementation of CT.
  4. Annotation information: Gene Ontology can be found from http://www.ebi.ac.uk/GOA/. ** Dimensional reduction: DMLDA_transform.m represents the DMLDA. MDDM_transform.m represents MDDM. PCA_transform.m represents PCA. MLSI_transform represents MLSI. MVMD_transform represents MVMD.

** Classifier: LIFT.m is the implementation of LIFT. MLKNN_test.m,MLKNN_train.m are the implementation of MLKNN. ML_GKR.m is the implementation of ML_GKR. ML_RBF_train.m, ML_RBF_test.m is the implementation of ML_RBF. RankSVM_train.m,RankSVM_test.m is the implementation of RankSVM. orderSynthetic.m, ProSVM.m is the implementation of ProSVM.

** independent_test: The independent_test file contains the code of the test of independent dataset.
And you can run the demo.m in MATLAB.

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  • MATLAB 98.2%
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