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BIB-Autologous-Tissue-Graft-Culture-ATGC

Overview

Our team is growing human skin cells

Abstract

In This paper our team will dicuss our protocol for decellularizing different leaves from different organism, and replace the space with skin cells

Introduction

The Skin is the largest organ of our body, and it is import to researchers to understand the structure and functions of the skin. Skin is import for the cosmetic, pharmaceutical and medical industries. Due the the ethical concerns regarding research of skin, researchers are looking for ways to simulate the behavior of human skin.

Methods

The first protocol we did is the chemical decellularization for spinach leaves insert source here .

References

  1. Piasek AM, Levkovych I, Musolf P, Chmielewska H, Ścieżyńska A, Sobiepanek A. Building Up Skin Models for Numerous Applications - from Two-Dimensional (2D) Monoculture to Three-Dimensional (3D) Multiculture. J Vis Exp. 2023;(200):e65773. Published 2023 Oct 20. doi:10.3791/65773.

  2. Boston College. Decellularized spinach serves as an edible platform for laboratory-grown meat. https://www.bc.edu/bc-web/bcnews/campus-community/faculty/decellularized-spinach-lab-grown-meat.html#:~:text=Spinach%2C%20a%20cost%2Defficient%20and,online%20edition%20of%20the%20journal.

  3. Pappalardo A, Cespedes DA, Fang S, et al. Engineering edgeless human skin with enhanced biomechanical properties. Science Advances. 2023;9(4):eade2514. doi:10.1126/sciadv.ade2514.

  4. Levy MG. This Lab-Grown skin could revolutionize transplants. WIRED. Published February 21, 2023. https://www.wired.com/story/this-lab-grown-skin-could-revolutionize-transplants/.

  5. Smythe P, Wilkinson HN. The Skin Microbiome: Current Landscape and Future Opportunities. Int J Mol Sci. 2023 Feb 16;24(4):3950. doi:10.3390/ijms24043950. PMID: 36835363; PMCID: PMC9963692.

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