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Gut microbiome and fibrillatio atriorum

This repository contains our R code for gut microbiome and FA analysis. The file microbiomefa.Rmd is the main analysis while different helper functions are defined in separate R files.

The code calculates

  • cross-sectional microbial diversity (alpha and beta) at species level
  • draws cross-sectional PCoA plots at species level
  • checks cross-sectional associations between top bacterial genera and FA
  • Cox models for participants that don't have FA at baseline
    • associations between top genera and FA
    • associations between baseline PCA-axes and FA
    • associations between baseline alpha diversity and FA

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