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Detailed README
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lguillier committed Feb 24, 2019
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AB_SA
AB_SA - Source attribution based on accessory genes
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Predicts the source of bacterial strains based on their accessory genes.

## Contents
* [Introduction](#introduction)
* [Input data](#input-data)
* [Pangenome](#pangenome)
* [Genes enriched](#genes-enriched)

## Introduction

The AB_SA ("Accessory-based source attribution") method aims at attributing the origin of bacterial strains associated to human cases or isolated in environment.
AB_SA method relies on accessory genes and multinomial logistic model. AB_SA uses as input a list of enriched genes in the sources, it trains and tests the multinomial logistic model and can predict genomes of strains with unknown sources
AB_SA method relies on accessory genes and multinomial logistic model. AB_SA uses as input a list of enriched genes in the sources, it trains and tests the multinomial logistic model and can predict genomes of strains with unknown sources.


## Input data

### Pangenome
The pangenome of the strains (both strains from the sources and the strains to attribute) included in the study should be determined. The AB_SA method parses the Rtab produced by [Roary] (http://sanger-pathogens.github.io/Roary)

### Genes enriched

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