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AB_SA | ||
AB_SA - Source attribution based on accessory genes | ||
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Predicts the source of bacterial strains based on their accessory genes. | ||
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## Contents | ||
* [Introduction](#introduction) | ||
* [Input data](#input-data) | ||
* [Pangenome](#pangenome) | ||
* [Genes enriched](#genes-enriched) | ||
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## Introduction | ||
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The AB_SA ("Accessory-based source attribution") method aims at attributing the origin of bacterial strains associated to human cases or isolated in environment. | ||
AB_SA method relies on accessory genes and multinomial logistic model. AB_SA uses as input a list of enriched genes in the sources, it trains and tests the multinomial logistic model and can predict genomes of strains with unknown sources | ||
AB_SA method relies on accessory genes and multinomial logistic model. AB_SA uses as input a list of enriched genes in the sources, it trains and tests the multinomial logistic model and can predict genomes of strains with unknown sources. | ||
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## Input data | ||
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### Pangenome | ||
The pangenome of the strains (both strains from the sources and the strains to attribute) included in the study should be determined. The AB_SA method parses the Rtab produced by [Roary] (http://sanger-pathogens.github.io/Roary) | ||
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### Genes enriched |