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add models
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alfredyewang committed Apr 10, 2022
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30 changes: 30 additions & 0 deletions README.md
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Expand Up @@ -6,3 +6,33 @@ By leveraging paired whole genome sequencing data and epigenetic functional assa

<div align=center><img width="800" height="500" src="https://raw.githubusercontent.com/alfredyewang/DeepPerVar/main/src/DeepPerVar.jpeg"/></div>
</center>


## DeepPerVar

We implement a webserver to predict genome-wide H3K9ac signals and DNA methylation ratio and the mutation effect on these two epigenetics signals. The webserver can be accessed from [link].(http://35.202.146.70/). <br />
<br />

## Requirements and Installation

DeepPerVar is implemented by Python3.

- Python 3.8
- samtools 1.15.1
- hdf5 == 1.10.4
- numpy >= 1.18.5
- pytorch ==1.7.1

Download [Reference Genome (hg19)]() [DeepPerVar Models] (https://drive.google.com/file/d/1Q_EzL_R4MLHSPYXKIqGUeXkDNx1yJ4WB/view?usp=sharing)

```
unzip Base.zip
```

Download DeepPerVar:
```
git clone https://github.com/alfredyewang/DeepPerVar
```
Install requirements
```
pip3 install -r requirements --user
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- hdf5 == 1.10.4
- numpy >= 1.18.5
- pytorch ==1.7.1

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