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Update README.md
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rasools authored Feb 26, 2018
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Expand Up @@ -4,5 +4,5 @@ Toolbox for generating protein-secretion genome-scale model for Human.
To test this toolbox and generate a protein-specific genome-scale model you just need to run humanSec.m function. This function needs following inputs:
1) A model (HMR2 or HMR2-drived models)
2) Uniprot ID for your interested protein
3) Protein-Specific Information Matrix (there is a list of human proteins in excel format in repository named PSIM_HUMAN.xlsx). you can call this list using importPsimFromExcel.m function and then use it in humanSec.m function.
4) List of template reactions (there is a list of template reactions in excel format in repository named tempRxns_v01.xlsx). you can call this list using importTempRxnsFromExcel.m function and then use it in humanSec.m function.
3) Protein-Specific Information Matrix (there is a list of human proteins in excel format in repository named PSIM_HUMAN.xlsx). you can call this list using importPsimFromExcel.m function and then use output of this function in humanSec.m function.
4) List of template reactions (there is a list of template reactions in excel format in repository named tempRxns_v01.xlsx). you can call this list using importTempRxnsFromExcel.m function and then use output of this function in humanSec.m function.

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