Package: ASSIGN

Type: Package

Title: Adaptive Signature Selection and InteGratioN (ASSIGN)

Version: 1.3.6

Date: 2014-10-30

Author: Ying Shen, Andrea H. Bild, and W. Evan Johnson

Maintainer: Ying Shen [email protected]

Depends: Rlab, msm, gplots

Description: ASSIGN is a computational tool to evaluate the pathway deregulation/activation status in individual patient samples. ASSIGN employs a flexible Bayesian factor analysis approach that adapts predetermined pathway signatures derived either from knowledge-based literatures or from perturbation experiments to the cell-/tissue-specific pathway signatures. The deregulation/activation level of each context-specific pathway is quantified to a score, which represents the extent to which a patient sample encompasses the pathway deregulation/activation signature.

License: MIT

Imports: graphics, grDevices, stats, utils

biocViews: Software, GeneExpression, Pathways, Bayesian