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lh3 committed Nov 19, 2014
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```sh
# Download the bwa-0.7.11 binary package (download link may change)
wget -O- http://sourceforge.net/projects/bio-bwa/files/bwakit-0.7.11_x64-linux.tar.bz2/download \
wget -O- http://sourceforge.net/projects/bio-bwa/files/bwakit/bwakit-0.7.11_x64-linux.tar.bz2/download \
| gzip -dc | tar xf -
# Generate the GRCh38+ALT+decoy+HLA and create the BWA index
bwa.kit/run-gen-ref hs38d6 # download GRCh38 and write hs38d6.fa
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This generates `out.aln.bam` as the final alignment, `out.hla.top` for best HLA
genotypes on each gene and `out.hla.all` for other possible HLA genotypes.
Please check out [bwa/bwakit/README.md][kithelp] for details.
Please check out [bwa/bwakit/README.md][kithelp] for details. If the download
link above does not work, please acquire the binary package [here][res].

## Background

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[res]: https://sourceforge.net/projects/bio-bwa/files/
[res]: https://sourceforge.net/projects/bio-bwa/files/bwakit
[sb]: https://github.com/GregoryFaust/samblaster
[grc]: http://www.ncbi.nlm.nih.gov/projects/genome/assembly/grc/
[novel]: https://gist.github.com/lh3/9935148b71f04ba1a8cc
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