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Showing results

tests for statistical significance of clustering

R 37 6 Updated Nov 21, 2018

Analysis methods for analysing single cell RNA-seq data; particularly with the goal of checking if tentative clusters of cells are significantly different to one another in terms of their gene expr…

Jupyter Notebook 33 6 Updated Aug 10, 2023
Python 7 3 Updated Dec 5, 2024

TCR and BCR assembly from RNA-seq data

C 291 50 Updated Jan 3, 2025

In-depth analysis of normalization and transformation methods for building coexpression networks from RNA-seq data.

HTML 12 3 Updated Aug 4, 2023

Genotype-free demultiplexing of pooled single-cell RNA-Seq, using a hidden state model for identifying genetically distinct samples within a mixed population.

Python 41 9 Updated Feb 8, 2023

Clustering scRNAseq by genotypes

Python 174 46 Updated Nov 15, 2024

epiTCR: a highly sensitive predictor for TCR–peptide binding

Jupyter Notebook 10 5 Updated Aug 6, 2024

Clonotype Neighbor Graph Analysis

Jupyter Notebook 83 18 Updated Sep 12, 2024

Methods for clustering and analyzing high-throughput single cell immune cell repertoires (RepSeq)

C++ 15 4 Updated May 23, 2022
R 10 1 Updated Jun 28, 2024

Tutorial for STAR-Fusion, FusionInspector, and de novo reconstruction of fusion transcripts using Trinity

Perl 14 5 Updated Nov 21, 2019

Mouse cell atlas

R 60 17 Updated Apr 18, 2020

SCalable Inference of Regulatory Activity in Single Cell RNA-Seq data

R 5 5 Updated Jun 20, 2023

R package for Protein activity analysis of single-cell RNAseq.

R 79 24 Updated Dec 15, 2022

A tool for detecting somatic variants in single cell data

Python 182 28 Updated Sep 15, 2024

GREAT Analysis - Functional Enrichment on Genomic Regions

R 85 13 Updated Aug 9, 2024

TCRconv is a deep learning model for predicting recognition between T cell receptors and epitopes. It uses protBERT embeddings for the TCRs and convolutional neural networks for the prediction.

Jupyter Notebook 23 6 Updated Oct 18, 2022

ERGO-II, an updated version of ERGO including more features for TCR-peptide binding prediction

Python 29 8 Updated Apr 1, 2022

⚙️ Matching T-cell repertoire against a database of TCR antigen specificities

Groovy 38 7 Updated Nov 12, 2018
Python 37 7 Updated Aug 18, 2020

Code for "T Cell Receptor Specificity Prediction with Bimodal Attention Networks" (https://doi.org/10.1093/bioinformatics/btab294, ISMB 2021)

Jupyter Notebook 29 6 Updated Aug 4, 2023
C++ 27 12 Updated Nov 27, 2024

Deep Learning Methods for Parsing T-Cell Receptor Sequencing (TCRSeq) Data

Jupyter Notebook 115 40 Updated Feb 15, 2023

T/B cell receptor sequencing analysis notes

216 32 Updated Dec 1, 2024

ERGO is a deep learing based model for predicting TCR-peptide binding.

Python 18 3 Updated Aug 26, 2020

R toolkit for inference, visualization and analysis of cell-cell communication from single-cell data

R 656 149 Updated Jan 6, 2024

Code repository for the Tumor Immune Cell Atlas (TICA) project

R 62 13 Updated Mar 31, 2022

Interfaces for HDF5-based Single Cell File Formats

R 156 51 Updated Nov 4, 2023
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