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mlin authored Aug 27, 2020
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Expand Up @@ -8,11 +8,11 @@ spVCF is an evolution of VCF that keeps most aspects of its tab-delimited text f

Further resources:

* [bioRxiv preprint](https://www.biorxiv.org/content/10.1101/611954v1) for a short manuscript on the approach & tool
* [bioRxiv preprint](https://www.biorxiv.org/content/10.1101/611954v2) for a short manuscript on the approach & tool
* [doc/SPEC.md](https://github.com/mlin/spVCF/blob/master/doc/SPEC.md) has complete details and a worked example
* [doc/compression_results.md](https://github.com/mlin/spVCF/blob/master/doc/compression_results.md) tests spVCF with *N*=50K exomes, observing up to 15X size reduction for bgzip-compressed pVCF, and scaling much more gently with *N*.
* [slide deck](https://docs.google.com/presentation/d/13lzEkdWAVwcsKofhsiYEdl92xMQgx5_dSOSIyZDggfM/edit?usp=sharing) presented at the GA4GH & MPEG-G Genome Compression Workshop, October 2018.
* NEW: [spVCF files for the resequenced 1000 Genomes Project cohort](https://github.com/mlin/spVCF/blob/master/doc/1000G_NYGC_GATK.md) (*N*=2,504 WGS)
* [spVCF files for the resequenced 1000 Genomes Project cohort](https://github.com/mlin/spVCF/blob/master/doc/1000G_NYGC_GATK.md) (*N*=2,504 WGS)

## `spvcf` utility

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